D-Alanine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]- - Names and Identifiers
D-Alanine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]- - Physico-chemical Properties
Molecular Formula | C26H24N2O6
|
Molar Mass | 460.48 |
Density | 1.320 |
Storage Condition | 2-8°C |
Use | This product is for scientific research only and shall not be used for other purposes. |
D-Alanine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]- - Introduction
D-Alanine,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]-, also known simply as Fmoc-D-Ala-OBzl, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
1. Chemical formula: C31H29N3O6
2. molecular weight: 535.58g/mol
3. Appearance: white to light yellow solid
4. melting point: about 136-139 degrees Celsius
Use:
Fmoc-D-Ala-OBzl is often used as a protecting group in organic synthesis. This compound can be used to protect D-alanine residues during the synthesis of peptides and proteins to prevent side reactions with other reactants, thereby maintaining selectivity and yield. In addition, Fmoc-D-Ala-OBzl can also be used to synthesize and study drugs, peptides and bioactive molecules.
Preparation Method:
The preparation of Fmoc-D-Ala-OBzl usually involves the following steps:
1. D-alanine reacts with benzyl alcohol to generate D-Ala-OH.
2. D-Ala-OH reacts with fluorene formic acid, carbon dioxide and dimethylformamide to generate Fmoc-D-Ala-OH.
3. Fmoc-D-Ala-OH reacts with benzyl alcohol to generate Fmoc-D-Ala-OBzl.
Safety Information:
Fmoc-D-Ala-OBzl under normal conditions generally do not cause acute toxic effects on the human body, but still need to be used with caution. When operating, observe proper laboratory safety practices, such as wearing appropriate personal protective equipment. In addition, the compound should be stored in a dry, cool place and away from sources of fire, heat and oxidants.
Last Update:2024-04-09 20:52:54